Responsive polymeric mixed conductors for sensing and stimulation
Sahika Inal a
a KAUST: King Abdullah University of Science and Technology, 4700 King Abdullah University of Science and Technology, Thuwal, Saudi Arabia
Proceedings of Bioelectronic Interfaces: Materials, Devices and Applications (CyBioEl)
Limassol, Cyprus, 2024 October 22nd - 25th
Organizers: Eleni Stavrinidou and Achilleas Savva
Invited Speaker, Sahika Inal, presentation 030
Publication date: 28th June 2024

The ability to sense and react to environmental stimuli is a crucial material property to harness in the development of next-generation sensors, actuators, and robotics. In this presentation, I will introduce n-type conjugated polymers as multifunctional bioelectronic interfaces. Firstly, I will demonstrate how these polymers can be tailored to establish favorable interactions with catalytic enzymes. This biohybrid, when employed in an enhancement mode organic electrochemical transistor (OECT), exhibits remarkable sensitivity and selectivity in detecting glucose and lactate in blood serum or saliva across a broad concentration range. While highlighting the unique characteristics of these devices, I will delve into the potential pathways through which the polymer film generates charges and address stability concerns. Subsequently, I will explore how these polymer films respond to visible and near-infrared (NIR) light by generating voltage drops at the aqueous electrolyte interface. This system is then seamlessly integrated into an adaptable circuit with outputs controlled by various stimuli, effectively mimicking the function of a light-sensitive neuron. Finally, I will unveil a novel application of the n-type films, demonstrating their capacity to enhance stem cell maturation.

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