Transparent neuroelectronics for multimodal neural interfacing
Vasiliki Giagka a
a Delft University of Technology, Mekelweg, 4, Delft, Netherlands
Proceedings of Bioelectronic Interfaces: Materials, Devices and Applications (CyBioEl)
Limassol, Cyprus, 2024 October 22nd - 25th
Organizers: Eleni Stavrinidou and Achilleas Savva
Oral, Vasiliki Giagka, presentation 027
Publication date: 28th June 2024

Interacting with the human body using a range of modalities (i.e., electricity, light, ultrasound), holds great potential in increasing the resolution and specificity of neuromonitoring and neuromodulation. Neuroelectronic interfaces that are compatible with more than a single modality can serve as a valuable tool for neuroscientific research. This talk will describe recent research in the development of such multimodal neural interfaces. The first part of this talk will discuss the wafer-level fabrication and performance of optically transparent and MRI-compatible graphene-based in vivo and in vitro neural interfaces. Such interfaces enable concurrent optogenetic stimulation and electrophysiology, as well as two-photon imaging during electrical stimulation. The devices discussed here are fabricated using a unique transfer-free process which leads to a multi-layer graphene with the highest charge storage capacity among all reported CVD-graphene electrodes to date. During the second part, this talk will focus on the development of ultrasound-compatible neuroelectronics to enable systematic studies to elucidate the mechanisms of ultrasound neuromodulation. 

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