P-type Accumulation Mode Organic Electrochemical Transistor Biosensor for Xanthine Detection in Fish
Yunfan Lin a
a KTH Royal Institute of Technology, SciLifeLab, Tomtebodavägen 23, Solna, Sweden
Proceedings of Bioelectronic Interfaces: Materials, Devices and Applications (CyBioEl)
Limassol, Cyprus, 2024 October 22nd - 25th
Organizers: Eleni Stavrinidou and Achilleas Savva
Poster, Yunfan Lin, 046
Publication date: 28th June 2024

Food waste is a significant global challenge that must be addressed to achieve the Nations Sustainable Development Goals (SDGs). Food packages integrated with biosensors can show more accurate quality monitoring, compared to predetermined expiration dates which may cause unnecessary food waste. In this study, a novel biosensor was developed based on an organic electrochemical transistor (OECT) to monitor xanthine concentration that is related to the degradation process in meat and fish products. p-type conjugated polymer, p(g42T-TT), and xanthine oxidase (XOD) were used as channel material and biorecognition element respectively. The OECT-biosensor showed a linear range from 5 µM to 98 µM with a detection limit of 5 µM. The results of real sample tests indicate the accumulation of xanthine in fish meat over a degradation period of 0 to 6 days, while the interference test showed no significant signal from ascorbic acid and uric acid.  The success of the developed biosensors demonstrates their significant potential for future use in food packaging and point-of-care testing for food monitoring. 

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