Designing Mechanically Interlocked Molecules to Function in the Solid-State
Stephen Loeb a
a University of Windsor, Sunset Avenue, 401, Windsor, Canada
Proceedings of Dynamic Materials, Crystals and Phenomena Conference (DynaMIC23)
Fribourg, Switzerland, 2023 March 22nd - 24th
Organizers: Jovana Milic and Simon Krause
Keynote, Stephen Loeb, presentation 015
Publication date: 15th February 2023

Mechanically interlocked molecules (MIMs) consist of multiple molecular components held together by mechanical bonds. The large amplitude motion of one component relative to the other can be used to design a variety of molecular switches and molecular machines. These molecules are almost exclusively designed to function in solution where their dynamics can occur unimpeded by structural constraints or close contacts between MIM molecules. This is very important for low energy processes but severely limits cooperativity amongst MIMs. This presentation will outline how the mobile components of MIMs can be designed for organization into the porous crystalline lattices of metal-organic framework materials and made to function in the solid-state where there is a much higher degree of organization and potential for interaction and cooperative behaviour.[1] The focus will be on (i) macrocyclic ring rotation [2], (ii) large amplitude translation [3], (iii) molecular switching [4], and (iv) the precise placement and interaction between components with different dynamics [5].


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