Publication date: 21st July 2025
Ever since its discovery by Myers and Nealson in 1988, Shewanella oneidensis MR-1 and other electroactive bacteria (EAB) have kept fascinating bioelectrochemists and others for the microbe’s ability to respond to oxidizing potentials delivered by polarized electrodes via extracellular transfer of charges. Realizing EAB’s potential for industrial applications, such as bioelectrosynthesis, wastewater treatment, bioremediation, etc., synthetic chemists, material scientists and electrical engineers joined the efforts to maximize the benefits of such bioelectochemical systems, particularly by improving the bioelectrical connection.
In the first part of the talk I will give my perspective on the various materials science approaches to improve extracellular electron transfer (EET), including works of direct involvement, based on the well-known conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT)1, chemically-functionalized CNTs2 and a ferrocene-based redox polymer3,4. To facilitate discussions on cross-material comparisons, I will mostly focus on one bioelectrochemical (or other) aspect at a time, such as electrochemically active surface area or microbe attachment to electrode, evaluated for multiple materials interfaces.
In the second part, I will introduce and outline future possibilities of EET signal transduction by organic electrochemical transistors (OECT) based on PEDOT:PSS, including the limited number of works published after we first introduced the organic microbial electrochemical transistor (OMECT) concept five years ago5.
For both topics, I will also show the first insights from our newest results using an n-type conducting polymer.
The speaker acknowledges a grant from the Swedish MSCA Seal of Excellence program (Vinnova, grant 2017−03121), Sweden-Japan 150 Anniversary Grants (The Swedish Foundation for International Cooperation in Research and Higher Education, STINT, grant SJ2017-7405), the MIRAI project (STINT, grant SG2016-6522), contribution from the Office of Science, Office of Basic Energy Sciences, of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231and JSPS KAKENHI Grant Number JP23K13651. Furthermore, the speaker thanks Prof. Caroline Ajo-Franklin and Prof. Akihiro Okamoto for providing mutant strains, and Dr. Lin Su and Dr. Xizi Long for preparing bacteria for transfer.