From Routine to Advanced: The Importance of Structural Characterization in Nanomaterials Development
Raymond Schaak a
a Penn State University
Proceedings of MATSUS Spring 2026 Conference (MATSUSSpring26)
C1 Structural Foundations of Nanomaterials Properties
Barcelona, Spain, 2026 March 23rd - 27th
Organizers: Nadine Schrenker and Stefano Toso
Invited Speaker, Raymond Schaak, presentation 527
Publication date: 15th December 2025

Much of our understanding of nanoscale materials comes from characterization techniques that reveal important aspects of structure, composition, morphology, and properties, among many other features. Structural characterization is particularly important, as crystal structure plays a foundational role in defining many other features of nanomaterials, including those listed above. Advanced structural characterization techniques provide increasingly sophisticated insights into how atoms are arranged within nanoscale materials. However, most researchers continue to emphasize routine structural characterization techniques that are readily available, such as powder X-ray diffraction. It is therefore important to fully harness the capabilities of such techniques, as well as to understand and appreciate the limitations. This talk will highlight how powder X-ray diffraction, a mainstream technique that is routinely applied to nanoscale materials systems, can be used alongside other materials characterization techniques to provide useful information, including phase evolution during synthesis, sample purity, and validation that the bulk of a sample matches key features observed microscopically. These topics will be discussed within a backdrop of compositionally complex colloidal nanoparticles, including heterostructured and high-entropy systems, where powder X-ray diffraction provides insights that are both complementary to, and distinct from, those obtainable by electron microscopy.

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