Flexible and mechanically adaptive photovoltaics are emerging as a key platform for next-generation energy systems, enabling integration beyond rigid, planar modules into curved, lightweight, and conformable applications. This symposium focuses on the fundamental and applied challenges that arise when photovoltaic devices operate under extreme mechanical constraints. Topics include materials and interfaces for mechaniacally robust solar cells, strain- and deformation-induced effects on charge transport, recombination, and defect formation, as well as scalable fabrication strategies for flexible and large-area devices. The symposium further explores system-level considerations, including ultrathin and high specific power photovoltaics for wearables, indoor energy harvesting, and aerospace applications. By bridging materials science, device physics, processing, and system integration, this symposium aims to establish a comprehensive understanding of photovoltaic operation beyond the rigid device paradigm.