Metal exsolution is a synthesis route for supported metal nanoparticles that enables the activation of earth-abundant elements and the functionalization of oxide surfaces for versatile applications in catalysis. After more than a decade of research, considerable progress has been made in understanding metal exsolution pathways at the atomic level. Exsolution catalysts have demonstrated promise for in-situ regeneration, enhanced stability, and a reduced reliance on critical metals in energy conversion systems, contributing to sustainability goals. With a growing scientific community in this cross-disciplinary field, closer exchange among researchers is needed to clarify future directions and explore the next generation of exsolution catalysts. Therefore, the proposed symposium will bring together leading experts in heterogeneous catalysis, ceramic synthesis, and advanced materials characterization from both inside and outside the exsolution community. Topics will include not only recent breakthroughs in nanoparticle exsolution, but also a critical review of the current state of knowledge to refine the catalysts design principles followed in the community. The main goals are to identify shared challenges and synergies, clarify the role of metal exsolution in addressing key challenges in catalysis, and establish a common foundation in relevant thermodynamic and kinetic principles.